药物制剂系

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于艳艳

作者:金飞     日期:2023-10-11   点击数:2056  

师资介绍

姓名:于艳艳

性别:女

民族:汉族

出生年月:1988.09.22

职称:副教授

学历:博士

职务:无

研究方向:

主要研究方向DNA纳米技术在药物及体内代谢物分析中的应用。

主持或参加科研项目(课题):

(1)    江苏省科技厅,优秀青年基金,BK20211604,基于CRISPR技术的免疫层析试纸法用于SARS-CoV-2双靶标联合检测,2021-072024-0650万元,在研,主持

(2)    南京大学“生命分析化学国家重点实验室”开放基金,SKLACLS2013,变构响应型多信号三维DNA探针的构建及应用,2020-042022-035万元,已结题,主持

(3)    南通市科技局,社会民生面上,MS12021051CRISPR多通道响应新技术的开发及用于SARS-CoV-2可视化现场检测,2021-072023-0610万元,已结题,主持

(4)    南通市科技局,新型冠状病毒专项,XG202008-4,等温扩增式3D折纸芯片的研发及用于新型冠状病毒检测,2020-032022-024万元,已结题,主持

(5)    国家自然科学基金委员会,青年项目,21705082,纸基变构响应型三维传感界面的构建及其p53/MDM2相互作用抑制剂研究应用,2018-012020-1225万元,已结题,主持

(6)    江苏省科技厅,青年项目,BK201704443D折纸芯片传感系统的构建及用于p53/MDM2相互作用抑制剂的研究,2017-072020-0620万元,已结题,主持

(7)    中国博士后科学基金会,面上项目,2017M611640,集成式双信号响应型三维纳米探针的构建及传感应用,2017-012018-115万元,已结题,主持

(8)    南通市科技局,科技计划项目,MS12016023,基于DNA等温指数扩增的生物传感器用于卵巢癌的早期联合诊断,2016-102018-093万元,已结题,主持


代表性第一作者和通讯作者论文

 

(1)       Yuliang Kang#, Jiali Wang#, Wensi Zhang, Yuhang Xu, Bohui Xu, Guangbo Qu, Yanyan Yu*, Bing Yan*, Gaoxing Su*RNA extraction-free workflow integrated with a single-tube CRISPR-Cas-based colorimetric assay for rapid SARS-CoV-2 detection in different environmental matricesJournal of Hazardous Materials, 2023, 454131487,通讯,IF: 13.6

(2)       Mengting Xu#, Yuedong Zhu#, Yan Zhang, Bin Gong, Yuliang Kang, Gaoxing Su *Yanyan Yu*Split G-quadruplex-programmed label-free CRISPR-Cas12a sensing systemChemical Communications2023, 59, 7615-7618,通讯,IF: 4.9

(3)       Yuliang Kang, Gaoxing Su*Yanyan Yu*Jiajia Cao, Jiali Wang, Bing Yan*CRISPR-Cas12a-Based Aptasensor for On-Site and Highly Sensitive Detection of Microcystin-LR in FreshwaterEnvironmental Science & Technology2022, 56, 4101−4110,通讯,IF: 11.4

(4)       JialongWu, Yanyan Yu* and Gaoxing Su*Safety Assessment of 2D MXenes: In Vitro and In VivoNanomaterials2022, 12, 828,通讯,IF: 5.3

(5)       Gaoxing Su#, Min Zhu#, Diyuan Li, Mengting Xu, Yuedong Zhu, Yan Zhang, Hongyan Zhu, Feng Li*, Yanyan Yu*Multiplexed lateral flow assay integrated with orthogonal CRISPR-Cas system for SARS-CoV-2 detectionSensors and Actuators: B. Chemical2022371132537,通讯,IF: 8.4

(6)       Min Zhu#, Jianbin Pan#, Mengting Xu, Jiajia Cao, Yuedong Zhu, Hongyan Zhu, Gaoxing Su*, Yanyan Yu*P53-MDM2 interaction monitoring and inhibitors potency evaluation based on CRISPR-Cas12a sensing platformSensors and Actuators: B. Chemical2022361131710,通讯,IF: 8.4

(7)       Wei S. Zhang#Jianbin Pan#, Feng Li, Min Zhu, Mengting Xu, Hongyan Zhu, Yanyan Yu*, Gaoxing Su*, Reverse-Transcription Recombinase Polymerase Amplification Coupled CRISPR-Cas12a for Facile and Highly Sensitive Colorimetric SARS-CoV-2 Detection, Analytical Chemistry, 2021, 93 (8): 4126–41333,通讯,IF:7.4

(8)       Yanyan Yu#, Wei S. Zhang#, Yuehua Guo, Huaping Peng, Min Zhu, Dandan Miao, Gaoxing Su*, Engineering of exosome-triggered enzyme-powered DNA motors for highly sensitive fluorescence detection of tumor-derived exosomes, Biosensors and Bioelectronics, 2020, 167: 112482,一作,IF12.6

(9)       Yanyan Yu#, Zhongnan Huang#, Yao Zhou, Lihua Zhang, Ailin Liu, Wei Chen*, Jianhua Lin*, Huaping Peng*, Facile and highly sensitive photoelectrochemical biosensing platform based on hierarchical architectured polydopamine/tungsten oxide nanocomposite film, Biosensors and Bioelectronics, 2019, 126: 1-6,一作,IF12.6

(10)   Gaoxing Su#, Min Zhu#, Mengting Xu, Jianbin Pan, Yao Zhou, Hongyu Zhou, Wei S. Zhang, Yanli Tong*, Yanyan Yu*, Fluorescence resonance energy transfer-based DNA framework assembled split G-quadruplex nanodevices for microRNA sensing, Chemical Communications, 2020, 56 (88): 13583-13586,通讯,IF: 4.9

(11)   Min Zhu, Yanyan Yu*, Junfeng Zhu, Yao Zhou, Gaoxing Su, Hongyan Zhu, Yong Chen, Mingkai Liu*, Single nucleotide variant discrimination by toehold exchange spherical nucleic acids modulated on hierarchical molybdenum disulfide acanthospheres, Chemical Communications, 2020, 56 (61): 8599-8602,通讯,IF: 4.9

(12)   Dandan Miao, Yanyan Yu*, Yong Chen, Yin Liu, Gaoxing Su*, Facile Construction of i-Motif DNA-Conjugated Gold Nanostars as Near-Infrared and pH Dual-Responsive Targeted Drug Delivery Systems for Combined Cancer Therapy, Molecular Pharmaceutics, 2020, 17 (4): 1127-1138通讯,IF: 4.9

(13)   Yanyan Yu, Yao Zhou, Min Zhu, Gaoxing Su*, Haohua Deng, Wei Chen*, Huaping Peng*, Dynamic split G-quadruplex programmed reversible nanodevice, Chemical Communications, 2019, 55 (3): 389-392一作,IF: 4.9

(14)   Yanyan Yu, Yao Zhou, Min Zhu, Mingkai Liu, Hongyan Zhu, Yong Chen, Gaoxing Su*, Wei Chen*, Huaping Peng*, Programming a split G-quadruplex in a DNA nanocage and its microRNA imaging in live cells, Chemical Communications, 2019, 55 (35): 5131-5134一作,IF: 4.9

(15)   Yanyan Yu#, Min Zhou#, Wei Zhang, Lei Huang, Dandan Miao, Hongyan Zhu*, Gaoxing Su*, Rattle-Type Gold Nanorods/Porous-SiO2 Nanocomposites as Near-Infrared Light-Activated Drug Delivery Systems for Cancer Combined Chemo–Photothermal Therapy, Molecular Pharmaceutics, 2019, 16 (5): 1929-1938一作,IF: 4.9

(16)   Yu Yanyan, Su Gaoxing, Zhu Hongyan, Zhu Qing, Chen Yong, Xu Bohui, Li Yuqin, Zhang Wei*. Proximity hybridization-mediated isothermal exponential amplification for ultrasensitive electrochemical protein detection, International Journal of Nanomedicine, 2017, 12: 5903-5914,一作,IF: 6.4

(17)   Yanyan Yu, Zuanguang Chen*, Wensi Jian, Duanping Sun, Beibei Zhang, Xinchun Li, Meicun Yao*, Ultrasensitive electrochemical detection of avian influenza A (H7N9) virus DNA based on isothermal exponential amplification coupled with hybridization chain reaction of DNAzyme nanowires, Biosensors and Bioelectronics, 2015, 64: 566-571,一作,IF: 12.6

(18)   Yanyan Yu, Zuanguang Chen*, Lijuan Shi, Fan Yang, Jianbin Pan, Beibei Zhang, Duanping Sun, Ultrasensitive Electrochemical Detection of MicroRNA Based on an Arched Probe Mediated Isothermal Exponential Amplification, Analytical Chemistry, 2014, 86 (16): 8200-8205,一作,IF: 7.4

(19)   Yanyan Yu, Zuanguang Chen, Sijing He, Beibei Zhang, Xinchun Li, Meicun Yao*, Direct electron transfer of glucose oxidase and biosensing for glucose based on PDDA-capped gold nanoparticle modified graphene/multi-walled carbon nanotubes electrode, Biosensors and Bioelectronics, 2014, 52: 147-152,一作,IF: 12.6

(20)   Yanyan Yu, Zuanguang Chen*, Beibei Zhang, Xinchun Li, Jianbin Pan, Selective and sensitive determination of uric acid in the presence of ascorbic acid and dopamine by PDDA functionalized graphene/graphite composite electrode, Talanta, 2013, 112: 31-36,一作,IF: 6.1